Captain Cristiano Ronaldo has been left out of Portugal's first squad since winning Euro 2016 as he continues his recovery from a knee injury.
The Real Madrid forward, 31, has not played since being substituted in the Euro 2016 final against France in July.
Portugal face Gibraltar in a friendly on 1 September before their 2018 World Cup qualifying campaign stats against Switzerland in Basel five days later.
Eder, who scored the winner in the Euro 2016 final, is in the 24-man squad.
Manager Fernando Santos has also included Southampton defenders Cedric Soares, 24, and 32-year-old Jose Fonte.
Squad
Goalkeepers: Rui Patricio (Sporting Lisbon), Anthony Lopes (Lyon), Eduardo (Dinamo Zagreb).
Defenders: Joao Cancelo (Valencia), Cedric Soares (Southampton), Pepe (Real Madrid), Bruno Alves (Cagliari), Jose Fonte (Southampton), Luis Neto (Zenit St Petersburg), Raphael Guerreiro (Borussia Dortmund), Eliseu (Benfica).
Midfielders: William Carvalho (Sporting Lisbon), Danilo (Porto), Joao Moutinho (Monaco), Adrien Silva (Sporting), Andre Gomes (Barcelona), Joao Mario (Sporting Lisbon), Renato Sanches (Bayern Munich).
Forwards: Rafa Silva (Braga), Bernardo Silva (Monaco), Nani (Valencia), Ricardo Quaresma (Besiktas), Eder (Lille), Andre Silva (Porto).

